[Gluten] US perspective on gluten-related diseases

e 1064

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US perspective on gluten-related diseases

Maureen M LeonardBrintha Vasagar

Abstract

The incidence of allergy and autoimmune disease in the US and other industrialized nations is increasing, and gluten-related disorders are no exception. The US has documented a profound rise in celiac disease that cannot be fully explained by improved serological techniques or better recognition by physicians. Non-celiac gluten sensitivity, a condition only recently recognized by the medical community, has become a commonly diagnosed entity. Proteins, including gluten are increasingly being identified as a source of wheat allergy. Although the gluten free diet represents a safe and effective treatment for these conditions, there is still much to be learned about the development of gluten-related disorders and the apparent increase in incidence within the US. In this article, we present a review of current knowledge on the epidemiology of gluten-related disorders within a global context, with a focus on diagnostic trends and the evaluation of potential risk factors.

제목

글루텐 관련 질환에 대한 미국의 관점

내용

미국 및 다른 선진국의 알레르성 질환 및 자가 면역 질환의 발병률이 증가하고 있으며 글루텐 관련 질환도 예외는아니다. 미국은 진보된 혈청학적 기법이나 의사의 더 나은 진단으로는 완전히 설명될 수 없는 셀리악병의발병률이 심오하게 증가함을 명시했다. 의학계에 의해 아주 최근에 공인된 질환인 비셀리악 글루텐 과민증은이제는 흔하게 진단되는 질병이 되었다. 글루텐 단백질은 밀 알레르기의 원인으로 점차 확인되고 있다. 글루텐 프리 식단은 이러한 질환을 위한 안전하고 효과적인 대표적인 치료법이지만, 글루텐 관련 질환의 발달 및 미국 내 명백한 발병률 증가에 관해 아직도 연구되어야 할 것이 많다. 이 글에서 우리는 진단 현황과 잠재적 위험 요소의 평가에 초점을 맞춰 글로벌 동향에서의 글루텐 관련 질환의역학에 대한 현 지식에 대해 검토한다.

글루텐 관련 질환 정의에 대한 개관

1. 셀리악병 (Celiac disease)

2. 밀 알레르기 (Wheat allergy)

3. 비셀리악 글루텐 과민증 (Non-celiac gluten sensitivity)

4. 포진형 피부염 (Dermatitis herpetiformis)

5. 글루텐 실조 (Gluten ataxia)

6. 자폐증 스펙트럼 장애와 글루텐 (Autism spectrum disorders and gluten)

Keywords

: #Gluten #GlutenRelatedDisorders #CeliacDisease#NonCeliacGlutenSensitivity #WheatAllergy #GlutenIntolerance #GlutenAtaxia #GlutenFree#GlutenFreeDiet #Microbiome #Microorganisms #Microbes #Microbiota#GutMicrobiome #GutMicrobiota #GutMicrobes

#글루텐 #글루텐관련질환 #글루텐알러지 #밀알러지 #셀리악병 #글루텐민감성 #글루텐과민성 #글루텐감수성 #비셀리악글루텐민감성 #글루텐불내증 #글루텐실조#글루텐운동실조 #마이크로바이옴 #미생물총 #미생물군 #미생물유전자 #장내미생물 #장내미생물총 #장내미생물군

[출처: Leonard, M.M., & Vasagar, B. (2014). US perspective on gluten-related diseases. Clinicaland experimental gastroenterology, 7, 25.]

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㈜마이크로바이옴은 생명공학 최고의 기술력을 바탕으로 마이크로바이옴 산업의 성장과 발전의 선도적 역할을 하고 있는 대한민국 대표 마이크로바이옴 R&D 전문 기업입니다.

㈜마이크로바이옴은 생명공학 국가연구기관인 한국생명공학연구원과 마이크로바이옴 관련

상품에 대하여 공동연구개발 및 기술이전을 통하여 공동특허 출원과 마이크로바이옴 상품화에 성공하였고, 마이크로바이옴 글로벌 기업이 되기 위하여 연구개발을 지속하고 있습니다.

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